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Nicholas Marko, MD
  • Male
  • Houston, Texas
  • United States
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Nicholas Marko, MD's Page

Profile Information

Consultant, Other
Job Function:
Predictive Modeling, Data Mining, Biostatistics, Operations Research, Statistical Programming, Vizualization, Statistical Consulting, Medical Statistics, Artificial Intelligence
Short Bio:
Although I am a neurosurgeon subspecializing in neurosurgical oncology, my academic and entrepreneurial interests are diverse. I am eager to build meaningful collaborations with creative thinkers from academia, healthcare-related industries, and other, non-healthcare organizations in the private, public, and government sectors who are interested in using mathematical modeling and analysis of big data to revolutionize medicine or other advanced industries.

My research efforts and interests based on this theme are threefold. 1) I use probabilistic, mathematical modeling to develop tools capable of improving individualized risk prediction, informing more accurate medical and surgical decision-making processes, and developing data-driven population-based screening and management strategies for common diseases. 2) I apply mathematical models to genomic and epigenomic data to improve our understanding of the fundamental biology of disease processes. This includes nonlinear and chaotic modeling strategies of cancer, but it also includes integrating molecular and clinical data so that these types of analyses can be applied in a clinically-relevant fashion. 3) I use comparative effectiveness and econometric strategies to study the costs and benefits of alternate management strategies in an effort to maintain high-quality patient care while optimizing the efficiency of its delivery.

Innovation in all of these dimensions motivates my work. I believe that true innovation means changing the way that we think about the challenges we face and the strategies that we apply to confronting these challenges. My goal is to develop synergistic research and commercial partnerships with experts from both medical and non-medical disciplines to build collaborations that simultaneously advance our mutual strategic goals and objectives.

I completed my undergraduate and medical education at the George Washington University in Washington, DC. During this time I also spend one year as a Howard Hughes Institute Medical Student Fellow at The Institute for Genomic Research (TIGR) working with the computational biology and human gene expression groups. I completed my Neurosurgery residency training at the Cleveland Clinic in Cleveland, Ohio. I am currently the American Association of Neurological Surgeons William P. VanWagenen Fellow, working at Cambridge University in the United Kingdom, working at the interface of applied mathematics and translational oncology. Beginning in July of 2012 I will be a fellow in neurosurgical oncology at the MD Anderson Cancer Center in Houston, Texas.
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